Yankees Opening Day 2025. The yankees will play the milwaukee. Major league baseball unveiled the full schedule for 2025 regular season on thursday, and the yankees will open at home against the milwaukee brewers, with opening day set for thursday,.

The yankees will start the regular season in the bronx on march 27 when the brewers visit yankee stadium for opening day. The new york yankees have announced the bronx bombers’ 2025 regular season schedule, including a home opener on thursday, march 27 against the brewers at yankee stadium.